A large ozone hole means more ultraviolet exposure. TOMS tracks solar ultraviolet (UV-B radiation) measured at 290-320 nanometer wavelengths. Loss of stratospheric ozone has been linked to skin cancer in humans. Increased UV-B exposures for Southern continents can seriously impact phytoplankton and other species. Red is for high UV exposure and blue is for low UV exposure.
For more information, see: http://www.gsfc.nasa.gov/topstory/2003/1208toms.html